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url: https://teammaclean.github.io/pepdiff/
template:
bootstrap: 5
bootswatch: flatly
navbar:
structure:
left: [intro, reference, articles]
right: [search, github]
components:
articles:
text: Articles
menu:
- text: Getting Started
href: articles/basic_workflow.html
- text: "---"
- text: Analysis Methods
- text: GLM Analysis
href: articles/glm_analysis.html
- text: ART Analysis
href: articles/art_analysis.html
- text: Pairwise Tests
href: articles/pairwise_tests.html
- text: "---"
- text: Diagnostics
- text: Checking Model Fit
href: articles/checking_fit.html
- text: Diagnostic Plots
href: articles/diagnostic_plots.html
reference:
- title: Import & Data
desc: Import data and create pepdiff_data objects
contents:
- read_pepdiff
- combine_tech_reps
- import_data
- new_pepdiff_data
- validate_pepdiff_data
- print.pepdiff_data
- summary.pepdiff_data
- subset.pepdiff_data
- plot.pepdiff_data
- title: Analysis
desc: Run differential abundance analysis
contents:
- compare
- compare_glm
- compare_art
- compare_pairwise
- compare_pairwise_rankprod
- compare_within_strata
- significant
- get_peptide
- get_comparison
- title: Results
desc: Results class and methods
contents:
- new_pepdiff_results
- validate_pepdiff_results
- print.pepdiff_results
- summary.pepdiff_results
- plot.pepdiff_results
- long_results
- build_results_tibble
- build_pairwise_results
- title: Diagnostics
desc: Check model fit and convergence
contents:
- plot_fit_diagnostics
- extract_diagnostics
- extract_stored_residuals
- get_all_residuals
- print_diagnostic_summary
- title: Visualization
desc: Plot functions for data and results
contents:
- plot_pca
- plot_pca_simple
- plot_heatmap
- plot_volcano_new
- plot_volcano_bf
- plot_pvalue_histogram
- plot_fc_distribution_new
- plot_bf_distribution
- plot_distributions_simple
- plot_missingness_simple
- plot_quant_distributions
- plot_fc
- plot_kmeans
- plot_result
- volcano_plot
- p_value_hist
- fc_qqplot
- norm_qqplot
- missing_peptides_plot
- times_measured_plot
- title: Statistical Tests
desc: Individual test implementations
contents:
- test_wilcoxon
- test_bootstrap_t
- test_bayes_t
- test_rankprod
- jzs_bf_approx
- classify_bf_evidence
- calc_t_statistic
- calc_rank_product
- build_replicate_matrix
- title: Model Fitting
desc: GLM and ART model fitting internals
contents:
- fit_glm
- fit_art
- fit_and_extract_glm
- fit_and_extract_art
- extract_contrasts_glm
- extract_contrasts_art
- run_models
- has_sufficient_variation
- build_formula
- title: Data Utilities
desc: Helper functions for data manipulation
contents:
- assess_missing
- compute_missingness
- compute_design_summary
- times_measured
- fold_change_matrix
- matrix_data
- list2mat
- mean_fold_change
- log2_fc
- apply_fdr_by_comparison
- title: Legacy Functions
desc: Deprecated functions from earlier versions
contents:
- compare.data.frame
- compare_legacy
- compare_many
- compare_calls
- get_sig_rows
- estimate_result_clusters
- kmeans_by_selected_cols
- get_bootstrap_percentile
- get_wilcoxon_percentile
- get_kruskal_percentile
- get_rp_percentile
- get_percentile_lowest_observed_value_iterative
- select_columns_for_contrast
- min_peptide_values
- replace_vals
- metrics
- title: Internal Utilities
desc: Internal helper functions
contents:
- validate_factors
- validate_positive
- check_zeros
- is_useable
home:
links:
- text: peppwR (companion package)
href: https://github.com/TeamMacLean/peppwR